Archive for February, 2011

Hydranencephaly : a case study @ Kathmandu University Medical Journal

Kathmandu University Medical Journal (2010), Vol. 8, No. 1, Issue 29, 83-86

Hydranencephaly
Pant S1, Kaur G2, JK De3
1Medical Offi  cer, 2Associate Professor, 3 Professor and Head, Department of Obstetrics and Gynaecology, Manipal College of Medical Sciences

Abstract
Hydranencephaly is a rare congenital condition where the greater portions of the cerebral hemispheres and the corpus striatum are replaced by cerebrospinal fl  uid and glial tissue. The meninges and the skull are well formed, which is consistent with earlier normal embryogenesis of the telencephalon. Bilateral occlusion of the internal carotid arteries in utero is a potential mechanism. Clinical features include intact brainstem refl  exes without evidence of higher cortical activity. The infant’s head size and the spontaneous refl  exes such as sucking, swallowing, crying, and moving the arms and legs may all seem normal at birth. However, after a few weeks the infant usually becomes irritable and has increased muscle tone and after a few months of life, seizures and hydrocephalus (excessive accumulation of cerebrospinal fluid in the brain) may develop. Other symptoms may include visual impairment, lack of growth, deafness, blindness, spastic quadriparesis (paralysis), and intellectual defi  cits. Since the early behaviour appears to be relatively normal, the diagnosis may be delayed for months sometimes. There is no defi  nitive treatment for hydranencephaly. The outlook for children with hydranencephaly is generally poor, and many children with this disorder die before their first birthday.

Key words: hydranencephaly, congenital anomaly, vascular disruption, thromboplastin,

Full reading @ kumj.com.np

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Intracranial Aneurysm with SLE treated by endovascular intervention@ Journal of Nepal Medical Association

Current Issue
Journal of Nepal Medical Association (JNMA)
JNMA | VOL. 49 | NO. 1 | ISSUE 177 | JAN-MAR, 2010

Intracranial Aneurysm with Systemic Lupus Erythematosus Treated by Endovascular Intervention  A CASE REPORT
Shrestha P, Sakamoto S, Shibukawa M, Kiura Y, Okazaki T, Kurisu K

ABSTRACT
Systemic Lupus Erythematosus (SLE) is a chronic disease with multiple pathologies that can affect every organ system of the body including central nervous system. Intracerebral aneurysms ad ubarachnoid Hemorrhages are one of the comparatively rarer manifestation of Central Nervous System SLE. Here we present a case of known SLE complicated by the rupture of intraerebral aneurysm atthe basilar artery ttip which was successfully treated with endovascular coiling.

Keywords: ceebral aneurysm, endovascular surgery, SAH, SLE

for complete pdf  http://www.jnma.com.np/

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Neuromedicine @ DovePress.com: Open access peer-reviewed scientific and medical journals

These journals cover the entire areas of neurological disease and research, from clinical neurology to sleep studies to laboratory experiments. And it is my recent favorites online journal website.

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My Recent Readings:
1. Brain ischemia and ischemic blood–brain barrier as etiological factors in sporadic Alzheimer’s disease  –  Review
Authors: Ryszard Pluta, Marzena Utamek, Poland
Published Date August 2008 , Volume 2008:4(5) Pages 855 – 864 DOI 10.2147/NDT.S3739

2. Brain ischemia and ischemic blood–brain barrier as etiological factors in sporadic Alzheimer’s disease -Review
Authors: Ryszard Pluta, Marzena Utamek, Poland
Published Date August 2008 , Volume 2008:4(5) Pages 855 – 864 DOI 10.2147/NDT.S3739

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